She was given as wife to G¬y¬k after Genghis Khan put down the rebellion of her clan in 1216-19. Oghul Qaimish bore G¬y¬k two sons, Khoja and Naqu. When her husband died in Qum-Sengir in Turkestan, she brought his ordo in the †gedeids&#39; appanage in Emil-Qobaq region in 1248. G¬y¬k&#39;s chief officials, Chinqai, Qadaq and Bala, helped Oghul to serve as regent. She spent her time with the Mongol shamans and lacked her mother-in-law, T¦regene&#39;s political skills. While her sons, Naqu and Khoja, and Shiremun, the grandson of †gedei, attempted to secure their claims on the throne, Chagatayid Khan Yes¬ M¦ngke primarily supported Oghul Qaimish.
Before or during the regency of Oghul, her husband&#39;s general Eljigidei sent the embassy to Louis IX of France to offer an alliance against the Muslims. Louis sent his men headed by Andr™ de Longjumeau in reply, but after she received them at her ordo on Emil, Oghul Qaimish sent them back with presents and letters announcing the Mongol demand for submission.
In 1249, Batu arranged a kurultai where M¦ngke was chosen as Khagan at Ala Qamaq in the Ulus of Jochi. Oghul declined Batu&#39;s invitation and sent Bala to that assembly with a demand that Shiremun or one of the †gedeids be elected khan. When the Toluids and the Golden Horde organized a second kurultai on the Kherlen River in 1251, which officially proclaimed M¦ngke Khan, Oghul Qaimish refused, with her son Khoja, to come. Most of the †gedeid and Chagataid princes supported her.
After her opponent, M¦ngke was elected in 1251, Oghul Qaimish&#39;s sons and Shiremun attempted to overthrow M¦ngke. When the plot was discovered, Khoja was exiled to the South China front and Shiremun was executed. Oghul Qaimish and Shiremun&#39;s mother Qadaqach were summoned to court and arrested. When Oghul Qaimish was stripped naked, she was angry with Sorghaghtani and other imperial females who questioned her in closed ger. After torture she was executed by being wrapped in felt and flung into a river.